Table 4.
Concentrations of inflammatory markers before and after the dietary challenge (Pooled mean values and standard deviations)*
| Time | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0 h | 1 h | 3 h | 6 h | P | |||||||||
| Mean | sd | Mean | sd | Mean | sd | Mean | sd | Treatment | Time | Interaction | LLOD† | ||
| IL-6 (pg/ml) | 0·94 | 0·64 | 0·79 | 0·63 | 0·94 | 0·77 | 1·16 | 1·15 | 0·818 | 0·001 | 0·146 | 0·06 | |
| IL-8 (pg/ml) | 8·46 | 2·60 | 9·06 | 2·51 | 9·47 | 2·46 | 8·48 | 2·63 | 0·97 | 0·004 | 0·866 | 0·04 | |
| IL-10 (pg/ml) | 6·94 | 17·99 | 6·69 | 16·44 | 7·14 | 18·73 | 7·30 | 18·13 | 0·989 | 0·305 | 0·459 | 0·03 | |
| IL-17 (pg/ml) | 3·08 | 4·35 | 3·11 | 4·89 | 3·40 | 4·71 | 4·10 | 7·62 | 0·889 | 0·681 | 0·155 | 0·74 | |
| IL-18 (pg/ml) | 35·85 | 23·24 | 38·63 | 25·24 | 37·05 | 24·17 | 39·35 | 23·43 | 0·958 | 0·001 | 0·217 | 0·71 | |
| TNFα (pg/ml) | 1·95 | 0·82 | 1·99 | 0·79 | 2·03 | 0·79 | 2·07 | 0·89 | 0·836 | 0·001 | 0·267 | 0·04 | |
| MCP-1 (pg/ml) | 456·7 | 238·5 | 496·8 | 228·2 | 498·4 | 246·5 | 521·8 | 238·1 | 0·645 | 0·001 | 0·599 | 0·09 | |
| CRP (mg/l) | 4·57 | 5·00 | 4·72 | 5·32 | 4·46 | 5·42 | 4·52 | 5·21 | 0·588 | 0·256 | 0·414 | 1·33 × 10−6 | |
| SAA (mg/l) | 9·21 | 8·92 | 9·51 | 9·48 | 9·13 | 10·12 | 8·52 | 9·44 | 0·473 | 0·023 | 0·361 | 1·09 × 10−5 | |
| sICAM (mg/l) | 0·28 | 0·09 | 0·30 | 0·16 | 0·29 | 0·14 | 0·27 | 0·09 | 0·629 | 0·427 | 0·834 | 1·03 × 10−6 | |
| sVCAM (mg/l) | 0·42 | 0·10 | 0·45 | 0·22 | 0·46 | 0·20 | 0·42 | 0·13 | 0·637 | 0·317 | 0·467 | 6 × 10−6 | |
LLOD, lower limit of detection; MCP-1, monocyte chemotactic protein-1; CRP, C-reactive protein; SAA, serum amyloid-A; sICAM, soluble intracellular adhesion molecule; sVCAM, soluble vascular adhesion molecule.
*
Values are pooled means of both treatments since there was no treatment effect.
†
Values from Meso Scale Discovery.