Table 1. Summary of key results in this paper and other relevant results²⁵,²⁷,⁴⁶.

	Presence of 5-HT				Tonic neuron stimulation				Tonic muscle stimulation
	NS intact		NS defective		NS intact		NS defective		NS intact		NS defective
Pump rate	Rapid	Ref. 27	Slow	Ref. 27	Rapid	Ref. 25	Slow	Ref. 25	Rapid	Ref. 46	Rapid	Fig. 3
E1 spikes	Yes	Ref. 27	No	Ref. 27	Yes	Fig. 4B	Not Tested		No	Fig. 4A	Not Tested

References or figures for each observation are listed in the table. Tonic optogenetic stimulation of pharyngeal neurons causes rapid pumping with E1 spikes, representing activation of the neurogenic rhythm and mimicking rapid pumping in the presence of food. In contrast, tonic optogenetic stimulation of pharyngeal muscle causes rapid pumping without E1 spikes, representing activation of the myogenic rhythm and mimicking pumping seen in mutants with defective (but not abolished) rhythmic nervous system input onto pharyngeal muscle, such as eat-2 mutants. In these mutants, activation of the myogenic but not neurogenic rhythm increases pumping rate, as expected.