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. 2016 Mar 15;6:22883. doi: 10.1038/srep22883

Figure 2. Selected genes relevant to PCOS that were differentially expressed in cohort 1 and replicated in cohort 2.

Figure 2

(A) Expression data of selected genes from the Illumina HumanHT- 12 v4 Expression BeadChip array (cohort 1). (B) Replication of gene expression data from the array by qPCR in adipose tissue from 21 unrelated women with PCOS and 21 controls (cohort 2). Protein expression of CYP1B1 (C) and PPARG (D) in control (n=5) and PCOS (n=5) are presented. (E) Differential DNA methylation of biologically validated genes. Values for gene expression are mean ± SD and for proteins mean ± SEM. *P < 0.05 (*) P = 0.056. # Sample run on a different membrane.