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. 2016 Mar 15;7:41. doi: 10.1186/s13287-016-0293-4

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© Gubert et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Quantification of motor neurons in the anterior horn of the spinal cord. The number of NeuN-positive cells was quantified in week 12 in the presymptomatic injected animals a and in week 15 in the symptomatic injected animals b. Both saline-injected and BMMC-injected mice showed a decrease in the number of motor neurons compared with the wild-type mice at the time point analyzed. There was no difference in the number of motor neurons after the treatment with BMMC injected in week 9 or in week 14 c–e. Representative images of NeuN expression in wild-type mice c, saline-injected animals in week 9 d, and BMMC-injected animals in week 9 e. *p <0.01. Scale bar: 50 μm. BMMC bone marrow-derived mononuclear cells, WT wild-type