Fig. 5.

PIBF1 overexpression attenuated miR-203-induced inhibition of GC growth and Akt signaling. a Lentivirus-mediated PIBF1 overexpression was used to transfect into miR-203-treated GC cells for 72 h, and cell proliferative activity was examined by MTT assay. b The protein expression levels of PIBF1 and downstream factors including p-Akt, Akt, EGFR, and STAT3 were detected by western blotting. c Lentivirus-mediated PIBF1 was used to transfect into miR-203-treated GC cells for consecutive five days, and cell proliferative activity was examined by MTT assay. **P < 0.01, *P < 0.05