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. 2016 Mar 15;15:53. doi: 10.1186/s12934-016-0451-5

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© Kildegaard et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Production of 3HP in S. cerevisiae strains with cofactor engineering. a 3HP titer in the recombinant strains grown in defined mineral or feed-in-time media. Error bars represent the standard deviations in 12 biological replicates. b The redox cofactor ratios in the 3HP producer strains grown in defined mineral medium for 24 h. Displayed are the average values ± standard deviations from biological triplicates. All the constructed strains carried the overexpression of ALD6, SEacs ^L641P, PDC1, and TY4-CaMCR–ACC1 ^**