Table 5.

Risk factors of mortality in patients with monoclonal gammopathy on chronic dialysis

Characteristic	Median Survival (mo) or Hazard Ratio	95% Confidence Interval	Log–Rank P Value
Univariate analysis
Men	17.93	15.51 to 20.39	0.47
Women	18.33	15.87 to 21.7
ALA	28.92	23.70 to 34.75	Reference
LCDD	18.39	14.85 to 24.10	0.15
MCN	16.00	12.52 to 18.33	0.001
Hemodialysis	18.33	16.36 to 20	0.65
Peritoneal dialysis	15.57	5.54 to 30.39
No catheter	28.03	23.87 to 32.30	<0.001
Catheter	16.49	13.93 to 18.82
No dialysis start in emergency	20.23	18.30 to 25.28	<0.01
Dialysis start in emergency	14.85	11.61 to 19.34
No chronic lung disease	18.43	16.69 to 20.39	0.06
Chronic lung disease	16.23	9.87 to 21.70
No cerebrovascular disease	18.07	16.22 to 20	0.96
Cerebrovascular disease	19.54	10.43 to 30.07
No congestive heart failure	19.67	17.93 to 22.75	<0.001
Congestive heart failure	10.16	8.16 to 12.82
No coronary artery disease	18.59	16.69 to 20.59	0.10
Coronary artery disease	16.23	10.30 to 20.13
No peripheral vascular disease	18.39	16.36 to 20.23	0.41
Peripheral vascular disease	15.87	9.02 to 22.62
No diabetes	18.75	16.95 to 20.72	0.26
Diabetes	13.97	9.48 to 19.93
No high BP	16.69	14.03 to 19.93	0.10
High BP	19.34	17.34 to 23.21
BMI>20 kg/m2	24.39	19.90 to 28.66	0.01
BMI<20 kg/m2	16.62	11.21 to 23.61
Frailty	5.15	4.07 to 6.82	<0.001
No frailty	23.61	20.49 to 27.38
No cardiac arrhythmia	18.72	16.49 to 20.72	0.05
Cardiac arrhythmia	17.11	10.49 to 21.70
Multivariate analysis
Age per yr	1.03	1.02 to 1.03	<0.001
Frailty	1.93	1.58 to 2.36	<0.001
Congestive heart failure	1.54	1.23 to 1.93	<0.001
Catheter	1.40	1.11 to 1.75	0.004
Year of RRT initiation per yr	0.95	0.91 to 0.99	<0.01
High BP	0.80	0.67 to 0.97	0.02

ALA, immunoglobulin light chain amyloidosis; LCDD, light–chain deposition disease; MCN, myeloma cast nephropathy; BMI, body mass index.