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. 2016 Jan 4;11(3):413–422. doi: 10.2215/CJN.07900715

Figure 1.

Figure 1.

Soluble TNF–like weak inducer of apoptosis (sTWEAK) levels, atherosclerotic burden, and vascular calcification in patients with CKD without any history of cardiovascular disease. (A) Box plots showing the difference in sTWEAK serum concentrations [median (IQR)] in parallel to stages of eGFR. P for trend <0.001. VD, CKD stage 5 dialysis. *P<0.001 versus CKD stage 3; †P<0.001 versus CKD stages 4 and 5. (B) Box plots showing sTWEAK levels (medians and interquartile ranges) according to the vascular territory affected. No plaques, n=329; carotid plaques, n=193; femoral plaques, n=116; both, n=420. *P<0.001 versus no plaques. (C) Box plots showing sTWEAK levels (medians and interquartile ranges) according to the presence of calcified carotid atherosclerotic plaques. Noncalcified carotid plaques, n=455; calcified carotid plaques, n=158. Whiskers represent 10th and 90th percentiles. *P<0.001 versus noncalcified carotid plaques.