Table 2.
Unadjusted and adjusted risks of postdischarge mortality stratified by eGFR and BUN at discharge
| End Point and Group | No. of Patients | No. of Patients with Events (%) | Unadjusted HR | 95% CI | P Value | Adjusted HR | 95% CI | P Value | P Value for Interactiona |
|---|---|---|---|---|---|---|---|---|---|
| All-cause death | |||||||||
| eGFR≥45 and BUN<25 | 1981 | 245 (12.5) | 1.00 | 1.00 | 0.004 | ||||
| eGFR≥45 and BUN≥25 | 418 | 87 (20.8) | 1.84 | 1.44 to 2.35 | <0.001 | 1.34 | 1.04 to 1.73 | 0.02 | |
| eGFR<45 and BUN<25 | 569 | 91 (15.8) | 1.33 | 1.05 to 1.70 | 0.02 | 0.97 | 0.76 to 1.26 | 0.84 | |
| eGFR<45 and BUN≥25 | 1481 | 439 (28.8) | 2.71 | 2.32 to 3.17 | <0.001 | 1.58 | 1.33 to 1.88 | <0.001 | |
| Cardiac death | |||||||||
| eGFR≥45 and BUN<25 | 1981 | 130 (6.6) | 1.00 | 1.00 | 0.002 | ||||
| eGFR≥45 and BUN≥25 | 418 | 46 (11.0) | 1.83 | 1.31 to 2.56 | <0.001 | 1.31 | 0.96 to 1.85 | 0.08 | |
| eGFR<45 and BUN<25 | 569 | 42 (7.4) | 1.17 | 0.83 to 1.66 | 0.37 | 0.85 | 0.59 to 1.24 | 0.41 | |
| eGFR<45 and BUN≥25 | 1481 | 246 (16.6) | 2.94 | 2.37 to 3.63 | <0.001 | 1.83 | 1.45 to 2.31 | <0.001 |
HR, hazard ratio; 95% CI, 95% confidence interval.
a
P value for interaction was obtained from the model including a product term of eGFR as a continuous variable and BUN as a dichotomous variable.