Table 3.
Results of survival analysis
| Factors | Univariate | Multivariate | Risk ratio | 95 % CI |
|---|---|---|---|---|
| (p value) | (p value) | |||
| Gender (Male vs Female) | <0.001 | <0.001 | 2.40 | 1.55–3.81 |
| Age (≥70 years) | <0.001 | <0.001 | 2.55 | 1.78–3.69 |
| PS (2 vs. 0–1) | <0.001 | 0.036 | 1.85 | 1.04–3.09 |
| H–J classification (3 vs. 1–2) | 0.070 | – | – | – |
| Smoking | 0.001 | 0.487 | – | – |
| ABG (Abnormal vs. Normal) | 0.002 | 0.006 | 1.61 | 1.14–2.26 |
| Predicted post PFTa) | 0.016 | 0.059 | – | – |
| Histology (others vs. Ad) | 0.017 | 0.011 | 1.65 | 1.12–2.44 |
| Differentiation (m/p vs well) | <0.001 | 0.014 | 1.71 | 1.11–2.71 |
| p-Stage (IB vs IA) | <0.001 | 0.002 | 1.74 | 1.23–2.48 |
| Operative proceduresb) | 0.470 | – | – | – |
| Location | 0.268 | – | – | – |
| Postoperative complication | 0.017 | 0.320 | – | – |
| Adjuvant therapy | 0.629 | – | – | – |
| Preoperative comorbidities | ||||
| Hypertension | 0.533 | – | – | – |
| Diabetes mellitus | 0.652 | – | – | – |
| eGFR (<60 ml/min/1.73 m2) | 0.078 | – | – | – |
| Child-Pugh classification (B or C) | 0.031 | 0.389 | – | – |
| Cardiac disease | 0.011 | 0.241 | – | – |
| Cerebral disease | 0.010 | 0.594 | – | – |
| Any prior tumors | <0.001 | <0.001 | 3.49 | 2.37—5.10 |
eGFR estimated glomerular filtration rate; m/p moderate or poorly
aPredicted postoperative values of FEV1.0 or DLco <40 % is defined as high-risk for PFTs
bOperative procedures, lobectomy versus more than lobectomy