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. 2016 Mar 15;6:10. doi: 10.1186/s13601-016-0098-7

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© Santos and Lack. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Basophil reactivity and basophil sensitivity. Two examples of dose–response curves of basophil activation following stimulation with various concentrations of allergen from two different patients are represented. The proportion of CD63+ positive cells is a measure of basophil reactivity and EC₅₀, the effective concentration at 50 % of the maximal activation, is a measure of basophil sensitivity