Table 1.
Distribution of the patients enrolled, grouped by age at diagnosis (group A, 5 to 10 years, versus group B, 11 to 16 years of age at diagnosis), by type of Inflammatory Bowel Disease, gender and ethnicity. Disease location, CD behaviour, Growth (for CD) and Severity (for UC) are also displayed according to the Paris Classification [28]
| Age at diagnosis | Brita Group A (5 to 10 years) | Brit Group B (11–16 years) | Itab Group A (5 to 10 years) | Ita Group B (11–16 years) |
|---|---|---|---|---|
| Patients’ number | 40 | 40 | 40 | 40 |
| Distribution by gender | 23 Mc 17 Fd | 25 M 15 F | 15 M 25 F | 20 M 20 F |
| Age at diagnosis | ||||
| Mean ± SDe | 7.65 ± 2.38 | 14.1 ± 1.03 | 7.4 ± 3.1 | 13.4 ± 1.39 |
| Median | 8.34 | 14.3 | 7.9 | 13.5 |
| Range | 5.1–10.6 | 11.4–16.6 | 5.6–10.8 | 11.2–16.3 |
| Distribution by type of IBDf | 15 CDg | 19 CD | 16 CD | 22 CD |
| 4 IBD-Uh CD-like | 5 IBD-U CD-like | 1 IBD-U CD-like | 1 IBD-U CD-like | |
| 12 UCi | 7 UC | 15 UC | 15 UC | |
| 9 IBD-U UC-like | 9 IBD-U UC-like | 8 IBD-U UC-like | 2 IBD-U UC-like | |
| Follow-up duration (years) | ||||
| Mean ± SD | 3.1 ± 2.3 | 1.92 ± 1.19 | 4.5 ± 3.71 | 2.21 ± 2.4 |
| Median | 2.8 | 1.72 | 4.2 | 1.17 |
| Range | 0.1–11.14 | 0.3–4.62 | 0.04–11.7 | 0.07–9.5 |
| Ethnicity | 36 white British | 38 white British | 34 white Italians | 38 white Italians |
| 3 white non-British (Belgium, Italy, Romania) | 1 white non British (Turkey) | 6 white non-Italians (2 from Romania, 2 from Moldova, 1 from Kosowo, 1 Gipsy) | 1 white non-Italian (Romania) | |
| 1 African (Morocco) | 1 African (Egypt) | 1 African (Morocco) | ||
| Disease location (Paris Classification [28]) | CD | CD | CD | CD |
| 2 L1 + L4a | 1 L1/2 L1 + L4a/1 L1 + L4b | 1 L1 | 2 L1/2 L1 + L4a | |
| 2 L2/4 L2 + L4a | 1 L2 + L4a | 5 L2/1 L2 + L4a | 1 L2/1 L2 + L4a | |
| 9 L3 + L4a/2 L3 + L4b | 3 L3/16 L3 + L4a | 3 L3/7 L3 + L4a | 10 L3/7 L3 + L4a | |
| UC | UC | UC | UC | |
| 1 E1/2 E2 | 1 E1/2 E2 | 1 E1/7 E2 | 2 E1/4 E2 | |
| 1 E3/17E4 | 2 E3/11 E4 | 1 E3/14 E4 | 2 E3/9 E4 | |
| CD behaviour (Paris Classification [28]) | 11 B1, 5 pB1 | 11 B1, 4 pB1 | 10 B1, 2 pB1 | 5 B1, 5pB1 |
| 1 B2 | 5 B2 | 1 B2, 1 pB2 | 10 B2, 1 pB2 | |
| 1B3 | 1 B3, 1 pB3 | 1pB3 | 1 pB3 | |
| 1pB2B3 | 1 B2B3, 1 pB2B3 | 1 B2B3, 1 pB2B3 | 1 B2B3 | |
| CD growth (Paris Classification [28]) | 4 S1 | 3 S1 | 3 S1 | 2 S1 |
| 17 S0 | 13 S0 | 20 S0 | 15 S0 | |
a Brit British
b Ita Italian
c M male
d F female
e SD standard deviation
f IBD inflammatory bowel disease
g CD Crohn’s disease
h IBD-U inflammatory bowel disease unclassified
i UC ulcerative colitis