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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Exp Neurol. 2015 Nov 4;275(Pt 1):59–68. doi: 10.1016/j.expneurol.2015.11.002

Figure 5. WKY Rats Show Reduced NR2A Protein Expression in the PL Cortex.

Figure 5

Anxiety vulnerable rats express lower levels of NR2A protein in the prelimbic (PL) cortex. Protein expression of NMDA receptor subunits was assessed in the PL cortex of naïve Sprague Dawley (SD, n=6) and Wistar Kyoto (WKY, n=6) rats. A) Representative blots of NMDA receptor subunits from the PL cortex of 2 SD and 2 WKY rats. B) Compared to SD rats (open bars), WKY rats (closed bars) express significantly less NR2A protein. This result was specific to the NR2A subunit, as strain differences were not observed in NR1 or NR2B protein levels. *p<0.05.