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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Exp Neurol. 2015 Nov 4;275(Pt 1):59–68. doi: 10.1016/j.expneurol.2015.11.002

Figure 6. Confirmation of PL Cortex Lesions.

Figure 6

Ibotenic acid lesions were made to the prelimbic (PL) cortex of Sprague Dawley (SD) and Wistar Kyoto (WKY) rats prior to avoidance training. Accuracy of lesions was confirmed for each subject. A) Diagram illustrating the smallest (black) and the largest (gray) lesion observed. Representative photomicrographs of lesion (B) and sham (C) rats reveal that ibotenic acid lesions resulted in significant cell loss and disruption of cortical layers with the PL cortex.