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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Exp Neurol. 2015 Nov 4;275(Pt 1):59–68. doi: 10.1016/j.expneurol.2015.11.002

Table 1. Amino acid neurotransmitters levels in the prelimbic (PL) cortex of WKY and SD rats.

Amino acid neurotransmitters levels in the PL cortex do not differ between strains. Basal levels of serine, glycine, glutamate, and GABA were assessed in naïve Sprague Dawley (SD, n=6) and Wistar Kyoto (WKY, n=8) rats by microdialysis and high-performance liquid chromatography with electrochemical detection (HPLC-EC). All values are based on a standard and have been corrected for differences probe efficiency. No significant differences were observed in neurotransmitter levels between strains; however, glutamate did trend lower in WKY rats. P-values were generated by independent samples t-test.

SD (n=6) WKY (n=8) p-value
Serine 4.29a±0.51 4.54±0.88 0.631
Glycine 146.11±18.13 163.23±28.95 0.544
Glutamate 13.89±3.68 7.27±0.99 0.072
a

Units are pmol/ml