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. Author manuscript; available in PMC: 2016 Mar 15.
Published in final edited form as: Growth Factors. 2015 Jun 26;33(3):192–199. doi: 10.3109/08977194.2015.1054990

Table 1.

Mean body weight, blood glucose and intraocular pressure (IOP) in control (Ctrl) and diabetic (STZ) rats left untreated or treated with 1mM Compound 49b alone or in combination of IGFBP-3 siRNA (Bp3siRNA) or scrambled siRNA (ScsiRNA) for 2 months and 7 days.

Groups Number Body weight (g) Glucose (mg/dl) IOP (mmHg)
Ctrl 15 458±18.6 86.7±8.2 14.6±2.8
STZ 10 236±32.5* 487.3±102.2* 13.8±4.3
STZ+49b 10 238±29.8* 523.5±70.8* 13.5±2.8
STZ+BP3siRNA 9 232±24.3* 511±52.1* 14.1±2.6
STZ+BP3siRNA+49b 10 229±21.5* 501.5±58.2* 16.3±3.1
STZ+ScsiRNA 8 233±25.2* 491±92.7* 14.5±3.3
*

p<0.05 versus control (Ctrl).