Fig. 5.

Ontology analysis of genes differentially expressed during development of murine heart. a The ontological terms were revealed by gene set enrichment analysis for the genes showing at least a two-fold change in expression at d7 (blue), w2 (yellow) and w8 (red) in comparison to d1. Gene set enrichment analyses were performed and gene ontology annotations were found with ClueGo. The results are presented as -log(P-value). The numbers of differentially regulated genes are shown in the inset. b Transcription factor binding sites enriched for the differentially regulated genes between d1 and d7 (blue), d1 and w2 (yellow), and d1 and w8 (red). The analysis was carried out with iRegulon. The results are presented as Normalized Enrichment Scores (NES). The numbers of genes associated with the listed terms/transcription factors are shown in parentheses