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. 2016 Mar 14;212(6):633–646. doi: 10.1083/jcb.201508068

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© 2016 Randise-Hinchliff et al.

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Figure 4. — Interchromosomal clustering of INO1 alleles is regulated by Rpd3(L). (A) Confocal micrographs of diploid cells having LacO arrays at each allele of INO1, expressing GFP-LacI and mCherry-ER marker. (B–D) Distances between INO1 alleles were measured and binned into 0.2-µm bins, and the distribution of distances within the population was compared. In B and C, the p-value is from a Wilcoxon rank sum test comparing the distributions. In panels C and D, the gray line (wild-type [WT] control) is the distribution from B under the inducing condition. (D, inset) P-values from Wilcoxon rank sum test for the indicated comparisons. (E) From the same measurements used to generate the distributions in B–D, the percentage of cells in which the two alleles are within 0.55 µm of each other. P-values from Fisher exact test.