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. Author manuscript; available in PMC: 2016 Mar 15.
Published in final edited form as: Circ Heart Fail. 2014 Nov 16;8(1):33–40. doi: 10.1161/CIRCHEARTFAILURE.114.001615

Table 1.

Baseline characteristics of the studies included in meta-analysis

Gary et al
200416
Kitzman et
al 201017
Edelmann et
al 201118
Smart et al
201220
Alves et al
201219
Kitzman et
al 201321
Total participants
(control/training)
16/16 27/26 20/44 13/12 11/20 31/32
Women (%) 100 75 36 48 29 76
Caucasian (%) 59 70 NA NA NA 68
Mean age, years 68 ± 11 69.5 ± 5.5 65 ± 7 64.4 ± 6.4 62.9 ±10.2 70 ± 7
Mean Body mass
index, Kg/m2
33.5 ± 6.5 0.5 ± 6.5 31 ± 5 32.1 ± 6.4 28.4 ± 4.5 32.1 ± 6.6
NYHA Class II (%)

NYHA Class III (%)
41

59
51

21
84

16
64

0
39

55
51

49
Hypertension (%) 88 68 86 16 68 89
Diabetes (%) 31 17 14 16 35 24
Baseline Systolic BP,
mm Hg
NA 147± 20 140 ± 19 131±11 NA 146 ± 17
Baseline Heart Rate,
beats/min
NA 69 ± 13 66 ± 11 NA NA NA
Presentation EF (%) ≥ 45 ≥ 50 ≥ 50 ≥ 45 ≥ 55 ≥ 50
Exercise capacity
Assessment
6 min
walk test
Cycle
Ergometer
Cycle
Ergometer
Cycle
Ergometer
Exercise
treadmill test
Cycle
Ergometer
6 min walk at
baseline, feet
832 ± 366 1452 ± 332 1794 ± 282 NA NA 1450 ± 300
Peak oxygen uptake
baseline, ml/kg/min
NA 13.3 ± 2.6 16.3 ± 4.8 13.2 ± 3.9 13.6 ± 4.9 14.1± 3.0
Blinded assessment
of outcomes
No Yes Yes Yes Yes Yes

NYHA: New York Heart Association; BP: Blood Pressure; EF: Ejection Fraction; Data represented as mean ± SD