Table 2. RBC deformability indices using dual-beam optical tweezers for healthy control subjects and study subjects (diabetic retinopathy).
Control group | DM group | DR group | ||
---|---|---|---|---|
Total number of cell cycles (5–10cycles/cell) | 925 | 925 | 925 | |
Average unstretched cell size (μm) (SD, Range) | 8.45(±0.25, 8.03–9.25) | 8.68(±0.49, 7.33–10.27) | 8.82(±0.32, 8.03–9.62) | p < 0.001 |
Avergae maximal stretched cell size (μm) (SD, Range) | 9.04(±0.17, 8.55–9.65) | 9.23(±0.49, 7.82–10.56) | 9.39(±0.26,8.70–10.03) | p < 0.001 |
Average difference between stretched and unstretched cell size (μm) (SD, 95CI) | 0.59(±0.19, 0.57–0.60) | 0.56(±0.32, 0.49–0.51) | 0.56(±0.24, 0.55–0.58) | P = 0.009 |
Deformability Index (SD, 95CI) | 0.0698(±0.024, 0.068–0.072) | 0.0645(±0.03, 0.063–0.067) | 0.0635(±0.029, 0.062–0.066) | p < 0.001 |
SD- Standard deviation, DM- Diabetes mellitus, DR – Diabetic retinopathy