Figure 4. Transgene expression following in vivo minicircle and plasmid DNA transfections.

Luciferase activity 24 hours following oropharyngeal instillation of CD1 mice with LED-1 complexes containing pMC.Luc2 plasmid DNA or MC.Luc2 minicircle DNA at either equimolar or equal mass quantities. *P < 0.05; **P < 0.01; Kruskal-Wallis test followed by Dunn’s post-test analysis to assess significance. Values are background subtracted and bar represents median RLU/mg.