Figure 7. Cytokine response in BALF following in vivo minicircle and plasmid DNA transfections.

Concentration of (a) IL-12, (b) IFN-γ and (c) TNF-α cytokines in BALF following instillation of LED-1 vectors containing luciferase encoding minicircle or plasmid DNA. Water was used as a vehicle control. *P < 0.05; Kruskal-Wallis test followed by Dunn’s post-test used to assess significance. Bar represents median.