Table 2.
The NF1 site is not conserved across species
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Underlined nucleotides depict boundaries for the CTF/NF1 site. Shaded nucleotides are those that were mutated in the in vivo promoter analyses, both of which are conserved in all species. Conserved nucleotides across all 5 species are indicated by #. The TESS analyses of these sequences show that the CTF1/NF1 site is conserved in the rat, mouse and hamster but not in the rabbit and human. Bold text depicts the bases that contribute to loss of the NF1/CTF1 site in these species.