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. Author manuscript; available in PMC: 2016 Nov 15.
Published in final edited form as: Cancer Res. 2015 Sep 17;75(22):4876–4883. doi: 10.1158/0008-5472.CAN-15-0556

Table 4.

Association between combinations of CagA with VacA seropositivity and risk of gastric adenocarcinoma and its subtypes.

All gastric
adenocarcinoma
N (%)		 Controls
N (%)		 Adjusted1 OR
(95%CI)		 GCA
N (%)		 Controls
N (%)		 Adjusted1 OR
(95%CI)		 GNCA
N (%)		 Controls
N (%)		 Adjusted1
OR (95%CI)
No CagA or VacA 17 (6.3) 68 (13.0) Reference 12 (8.5) 30 (10.9) Reference 5 (4.9) 33 (16.9) Reference
VacA only 11 (4.0) 47 (9.0) 0.8 (0.3–2.1) 5 (3.5) 26 (9.4) 0.4 (0.1–1.5) 4 (3.9) 14 (7.2) 1.4 (0.2–7.9)
CagA only 48 (17.6) 112 (21.4) 1.6 (0.8–3.3) 27 (19.0) 54 (19.6) 1.2 (0.5–3.1) 16 (15.5) 41 (21.0) 2.1 (0.6–7.1)
Both CagA and VacA 196 (72.1) 297 (56.6) 2.8 (1.4–5.3) 98 (69.0) 166 (60.1) 1.6 (0.7–3.8) 78 (75.7) 107 (54.9) 5.1 (1.6–15.9)
1

Conditional logistic regression, adjusted for education (illiterate vs. otherwise), ethnicity (Turkmen vs. non-Turkmen), tobacco and opium consumption (ever vs. never), and wealth score as continuous variable.