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. Author manuscript; available in PMC: 2016 Mar 15.
Published in final edited form as: Vaccine. 2012 Feb 11;30(15):2516–2522. doi: 10.1016/j.vaccine.2012.01.090

Figure 2.

Figure 2

(A) A phylogenetic tree of the N1 proteins. The NA amino acid sequences of indicated viruses were aligned and plotted using the Mega software. The bar indicates the genetic distance. (B) Molecular surface structure of the NA of A/California/7/2009 (Protein Data Bank 5NSS, one monomer shown). The locations of the amino acids in the CA09 NA that are identical to both H5N1 strains (HK03 and VN04) but different from the two seasonal H1N1 strains (NC99 and SD07) are shown in green; the amino acids of the CA09 NA that are identical to the seasonal H1N1 strains but different from the H5N1 strains are shown in red. The amino acid positions are indicated by N2 numbering. The activity cavity (AC) is indicated and the catalytic sites are shown in wheat color. The picture was generated by using PyMOL software.