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. Author manuscript; available in PMC: 2016 Mar 15.
Published in final edited form as: Vaccine. 2012 Feb 11;30(15):2516–2522. doi: 10.1016/j.vaccine.2012.01.090

Table 3.

HA and NA antibody response and cross-reactivity in H3N2 LAIV immunized ferrets

Geometric mean NI serum titers of ferrets
immunized with 1 dose of LAIV
Test antigen* Pan99
H3N2		 CA04
H3N2		 Uru07
H3N2
Pan99 81 <8 <8
CA04 <8 16 8
Uru07 <8 32 64
Geometric mean serum HAI titers of ferrets
immunized with 1 dose of LAIV
Test antigen Pan99
H3N2		 CA04
H3N2		 Uru07
H3N2
Pan99 40 <8 <8
CA04 8 161 16
Uru07 <8 16 64
*

Reassortant H6 viruses bearing the NA from the indicated virus.

Groups of three ferrets were inoculated intranasally with 107 FFU/ml of the indicated LAIV viruses. Serum was collected 2 to 3 weeks after immunization. The NI titers were determined by NI assay against the H6 reassortants containing the indicated NA test antigen. The HAI titers were determined by HAI assay using turkey RBC and the indicated homologous viruses.