Figure 3. Effect of microvesicles derived from human mesenchymal stem cells on lung weight gain.
Perfusion with ventilation significantly increased the total lung weight by 150%. Administration of MSC MV (100 μL or 100 μL + 200 μL groups) significantly reduced lung weight by 20–25% as compared to the Control (Perfusion only) at T6. Data was normalized to the initial weight of the lung to account for any differences in baseline lung injury or weight. Data (normalized to T0) are presented as mean ± SD, N = 4–6 per group. *p significant by ANOVA versus T0.
