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Effect of microvesicles derived from human mesenchymal stem cells on lung (A) tracheal pressure and (B) compliance. Perfusion with ventilation significantly increased tracheal pressure at T6. Administration of either doses of MSC MV reduced the tracheal pressure to baseline, increasing the compliance of the lung compared to T0. Data are presented as mean ± SD, N = 4–6 per group. Abbreviations: Ab, antibody; MSC, mesenchymal stem cells; MV, microvesicles.
