. Author manuscript; available in PMC: 2016 Mar 15.

Published in final edited form as: Am J Transplant. 2015 Apr 6;15(9):2404–2412. doi: 10.1111/ajt.13271

Table 2.

Time dependent values of mean pulmonary arterial pressure

	Perfusion only	MSC MV μL	MSC MV 200 μL	MSC MV 200 μL+anti-CD44 Ab	MSC MV 200 μL+IgG
Time (hours)	(n = 6)	(n = 6)	(n = 6)	(n = 4)	(n = 4)
0			11.0 ± 6.3
1	12.2 [4.6;20.9]	9.0 ± 5.1	6.4 ± 2.3^*	9.6 ± 4.4	5.6 ± 2.0
2	5.4 [4.0;22.5]	7.9 ± 5.9	5.6 ± 2.2^*	9.1 ± 6.4	5.0 ± 1.8^*
3	8.4 [2.8;26.6]	11.2 ± 7.7	5.2 ± 2.2^*	9.4 ± 8.0	4.7 ± 1.4^*
4	7.2 [3.4;23.8]	8.5 ± 7.0	5.3 ± 2.7^*	9.7 ± 8.6	4.7 ± 1.3^*
5	8.2 [2.2;26.7]	9.3 ± 6.9	5.4 ± 3.0^*	10.0 ± 9.0	4.8 ± 1.2^*
6	7.0 [2.5;25.2]	9.3 ± 5.1	5.6 ± 3.0^*	10.7 ± 8.8	5.0 ± 1.3^*

Ab, antibody; MSC MV, microvesicles derived from mesenchymal stem cells.

Data are expressed as mean ± SD when normally distributed and as median [Q1;Q3] if not (in mmHg).

Pulmonary arterial pressure at T0 corresponds to the mean value of each group pooled together.

p significant by Student t-test vs T0.