. Author manuscript; available in PMC: 2016 Mar 15.

Published in final edited form as: Am J Transplant. 2015 Apr 6;15(9):2404–2412. doi: 10.1111/ajt.13271

Table 3.

Time dependent values of mean pulmonary vascular resistance

	Perfusion only	MSC MV 100 μL	MSC MV 200 μL	MSC MV 200 μL + anti-CD44 Ab	MSC MV 200 μL + IgG
Time (hours)	(n = 6)	(n = 6)	(n = 6)	(n = 4)	(n = 4)
0			44.7 ± 26.3
1	48.9 [17.9;83.4]	39.8 ± 28.7	25.5 ± 9.1^*	38.3 ± 17.6	22.5 ± 8.2
2	24.1 [16.0;89.2]	35.9 ± 32.1	22.2 ± 8.7^*	36.2 ± 25.7	20.1 ± 7.2^*
3	33.3 [11.0;105.5]	49.2 ± 36.8	20.8 ± 8.9^*	37.7 ± 32.0	18.9 ± 5.7^*
4	28.5 [13.8;94.4]	38.8 ± 37.5	21.0 ± 11.0^*	38.7 ± 34.4	18.7 ± 5.3^*
5	32.3 [8.9;105.9]	41.9 ± 37.1	21.8 ± 12.1^*	40.1 ± 36.1	19.2 ± 5.0^*
6	27.7 [10.0;100.2]	40.4 ± 25.2	22.3 ± 12.1^*	42.9 ± 35.5	19.8 ± 5.0^*

Ab, antibody; MSC MV, microvesicles derived from mesenchymal stem cells.

Data are expressed as mean ± SD when normally distributed and as median [Q1;Q3] if not (in mmHg.L⁻¹.min⁻¹). Pulmonary resistances at T0 correspond to the mean value of each group pooled together.

p significant by Student t-test vs T0.