Table 1.
Embryonic lethality resulting from knock out of redox-related genes
| Category | Essential | Nonessential |
|---|---|---|
| Transcription factors | ||
|
| ||
| p65 | Nrf2 | |
| HIF | RelB | |
| Ref-1 | p50 | |
| p52 | ||
| c-rel | ||
|
| ||
| Antioxidants | ||
|
| ||
| Nrx2 | CAT | |
| GSH | Prx | |
| Trx1 | GPx1 | |
| Trx2 | GPx2 | |
| GPx4 | GPx3 | |
|
| ||
| ROS inducers | ||
|
| ||
| LOX | ||
| COX | ||
| NOX | ||
| NOS | ||
| XO | ||