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Antibacterial Testing of lead compounds against polymyxin-susceptible (S) A. baumannii ATCC 19606 and polymyxin-resistant (R) 19606R
| Polymer N° |
Monomer/ Compound |
Quaternized (Y/N) |
DP | Initiator chain length |
MIC A. baumannii S (μg/mL) (Data from Table 1) |
MIC A. baumannii R (μg/mL) |
|---|---|---|---|---|---|---|
| - | Polymyxin B | - | - | - | 2 | >128 |
| 4 | DMAEA | N | 5 | 12 | 50 | 38 |
| 5 | DMAEA | Y | 27 | 2 | 500 | 375 |
| 7 | DMAEA | Y | 26 | 12 | 250 | 88 |
| 12 | DEAEA | N | 5 | 12 | 88 | 15 |
| 16 | DEAEA | Y | 5 | 12 | 250 | 20 |
