. 2015 Sep 28;24:170–179. doi: 10.1007/s40629-015-0065-1

Tab. 1.

Surface markers of Langerhans cells (LCs) and dermal dendritic cells (dDCs)

	Occupation	Murine surface markers		Human surface markers
LCs	2–4 % of epidermal cells	CD45⁺, MHC class II⁺, CD11c⁺, T/B/NK cell markers^–,	CD11b⁺, CD205⁺, Langerin/CD207⁺, E-cadherin⁺, EpCAM⁺, Birbeck granule⁺	CD45⁺, MHC class II⁺, CD11c⁺, T/B/NK cell markers^–	E-cadherin⁺, EpCAM⁺, Langerin/CD207⁺, Birbeck granule⁺, CD1a⁺
Monocyte derived dDCs	no data		CD64^low/+,CCR2⁺		CD14+
CD11b ⁺ cDCs	50–70 % of dDC pool		CD11b⁺, CD301b⁺, CCR2⁺, CD172a⁺, CX3CR1^mid		CD1c⁺
XCR1 ⁺ cDCs	10–20 % of dDC pool		XCR1⁺, Langerin/CD207⁺, CD205⁺, CD11b^–, CD301b^–, CD172a^–, CX3CR1^– CD103⁺ CD103^–		XCR1⁺, CD141⁺
DN cDCs	no data		CD11b^low, CX3CR1^hi, CCR2⁺, CD172a⁺		no data