Table 2. Most important regions discriminating between MHE and NHE subjects.
Clusters | Hemisphere | Brain regions | Custer size (voxel) | BA | MNI coordinates (x, y, z) | Peak w value | ||
---|---|---|---|---|---|---|---|---|
1 | Right | Inferior frontal gyrus | 137 | 47/13/6/22/44/38 | 60 | 3 | 6 | –0.012 |
Insular cortex | ||||||||
Superior temporal gyrus | ||||||||
Precentral gyrus | ||||||||
2 | Left | Supramarginal gyrus | 168 | 40/13/41 | –39 | –27 | 15 | –0.019 |
Insular cortex | ||||||||
Superior temporal gyrus | ||||||||
Postcentral gyrus | ||||||||
3 | Right | Supramarginal gyrus | 94 | 40/43/2/4 | 63 | –18 | 15 | –0.014 |
Postcentral gyrus | ||||||||
Precentral gyrus | ||||||||
Superior temporal gyrus | ||||||||
4 | Left | Inferior frontal gyrus | 53 | 44/6 | –57 | 9 | 21 | –0.007 |
Precentral gyrus | ||||||||
5 | Bilateral | Medial frontal gyrus | 638 | 32/6/8/24/9 | 3 | 15 | 42 | –0.013 |
Anterior cingulate cortex | ||||||||
Superior frontal gyrus | ||||||||
6 | Right | Middle frontal gyrus | 558 | 46/10/9 | 51 | 9 | 36 | –0.016 |
Superior frontal gyrus | ||||||||
Inferior frontal gyrus | ||||||||
7 | Left | Middle frontal gyrus | 86 | 46/10 | –51 | 33 | 21 | –0.008 |
Inferior frontal gyrus | ||||||||
8 | Left | Supermarginal gyrus | 91 | 39/40/22 | –54 | –63 | 18 | –0.013 |
Angular gyrus | ||||||||
Superior temporal gyrus | ||||||||
9 | Right | Supermarginal gyrus | 148 | 40 | –33 | –42 | 39 | –0.016 |
10 | Right | Inferior occipital gyrus | 587 | 20/19/37/18 | 45 | –3 | –42 | 0.018 |
Inferior temporal gyrus | ||||||||
Parahippocampal gyrus | ||||||||
Fusiform gyrus | ||||||||
Middle occipital gyrus | ||||||||
11 | Left | Middle frontal gyrus | 115 | 10/46 | –42 | 45 | 6 | 0.008 |
Inferior frontal gyrus |
Abbreviation: MHE, minimal hepatic encephalopathy; NHE, no hepatic encephalopathy; BA, Brodmann area; MNI, Montreal Neurological Institute; w, attribute weight for the peak voxel.