Fig 1. The sequence of SfDredd.

The predicted amino acid sequence of SfDredd is shown in alignment with Dredd homologs from Bombyx mori (BmDredd), Aedes aegypti (AeDredd) and Drosophila melanogaster (DmDredd-PE). The amino acid residues identical among 4 Dredds are indicated by white letters within black boxes, the amino acid residues identical among 3 Dredds are indicated by white letters within dark gray boxes, and the amino acid residues identical between 2 Dredds are indicated by black letters within light gray boxes. The alignment was performed using ClustalX 2.1 and modified by GeneDoc 3.2. Secondary structures were predicted using JPred3. Box: catalytic center, closed circles: conserved residues responsible for the catalytic reaction, black arrow: predicted cleavage sites.