Table 2.
Other outcome measures
| Outcome measure | Reference for studies used | Inter‐rater reliability | Test‐retest reliability | Sensitivity to change | Clinically meaningful change | Endorsement |
|---|---|---|---|---|---|---|
| Mood/behavioral | ||||||
| NPI | 6, 22, 23, 24, 25, 26, 27, 31, 32, 33, 34, and 36 | High | Moderate to high | Yes | 8 points | Recommended |
| CSDD | 31 | High | High | Yes | NE for dementia | Recommended |
| BPRS | 37 | Moderate | NE for dementia | NE for dementia | NE for dementia | Suggested |
| ADLs and QOL | ||||||
| ADCS‐ADL | 6, 25, 27, 38, and 36 | High | High | Yes | 2 points | Recommended |
| QOL‐AD | 7 | High | High | Yes | NE for dementia | Recommended |
| DAD | 22, 26, 33, and 34 | High | High | Yes | NE for dementia | Recommended |
| SE‐ADL | 26 | Moderate | NE for dementia | NE for dementia | NE for dementia | Suggested |
| PDQ‐39 | Not used | NE for dementia | Moderate | NE for dementia | Depends on subsection, but has been established | Suggested |
| UPDRS‐ADL | 31 and 37 | NE for dementia | NE for dementia | NE for dementia | NE for dementia | Listed |
| Global | ||||||
| CGI | 22, 29, 35, and 37 | Moderate | Moderate | Yes | NE for dementia | Recommended |
| ADCS‐CGIC | 6, 25, and 27 | NE for dementia | High | Yes | 1–2 points | Suggested |
| CIBIC+ | 24, 26, and 32 | Low | Moderate | Yes | NE for dementia | Suggested |
| Caregiver burden | ||||||
| ZBI | 6 and 30 | NE for dementia | High | Yes | 13 points | Suggested |
Endorsement definitions: (1) “Recommended”: The outcome measure has been applied to PDD patients and has been found valid, reliable, and responsive in psychometric studies in studies of PDD or other dementias; (2) “Suggested”: The outcome measure has been applied to PDD patients and psychometric studies are promising (“moderate” to “high” parameters), but not yet complete in dementia populations and/or some psychometric properties are suboptimal (“low”); and (3) “Listed”: The outcome measure has been applied to PDD patients, but psychometric studies have demonstrated disappointing data (“low” parameters) and/or have not yet been performed in dementia populations. NE, Not established.