Table 1.

Thermodynamic data^a for binding of the saturated fatty acids 2–5 to host 1.

Guest	Ka (M−1)	ΔG (kcal mol−1)	ΔH (kcal mol−1)	−TΔS (kcal mol−1)
2	6.75 x 103	−5.22	−5.13	−0.097
3	8.07 x 104	−6.70	−6.09	−0.602
4	3.25 x 105	−7.52	−6.52	−1.000
5	4.19 x 105	−8.08	−8.82	0.762

^aAll determinations at 298 K except guest 5 (313 K). Data is an average of three titrations with experimental errors between runs of < 5%. Sodium phosphate buffer concentration was 50 mM (pH = 11.5).