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. 2015 Oct 26;6(42):44239–44253. doi: 10.18632/oncotarget.6235

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Copyright: © 2015 Duan et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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(A) Gating strategies of circulating Tfh cells and their subsets in HCC and HC. (B) Percentage of CXCR5⁺CD45RA⁻cells in CD4⁺ lymphocytes in HCC (n = 21) and HC (n = 11). (C) IL-21 concentration in the co-culture supernatant of purified CXCR5⁺CD45RA⁻CD4⁺CD3⁺ and IgD⁺CD27⁻CD19⁺CD3⁻ cells. (D) Distribution of Th1-like, Th2-like, and Th17-like subsets in circulating Tfh cells in HCC and HC. (D) Ratio of Th1-/Th2-like Tfh subsets and Th17-/Th2-like Tfh subsets in HCC and HC. Red lines in (B), (D) and (E) show the median values.