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. 2015 Oct 26;6(42):44274–44288. doi: 10.18632/oncotarget.6236

Figure 1. 244-MPT suppresses anchorage-independent soft agar growth and decreases viability of either gefitinib-sensitive or -resistant NSCLC cell lines.

Figure 1

(A) Chemical structure of 244-MPT. (B) HCC827 or (C) H1975 lung cancer cells were treated or not treated with different concentrations of 244-MPT or gefitinib for 24, 48, 72 or 96 h and proliferation was estimated by MTS assay. (D) HCC827 or (E) H1975 lung cancer cells were treated with increasing doses of 244-MPT or with gefitinib (1 μM). Representative photographs are shown and data are presented as mean values ± S.D. from triplicate experiments. The asterisk (*) indicates a significant (p < 0.05) decrease in colony formation compared to the control group.