Figure 6. miR-222 reduces DDP resistance and migration/invasion in TSCC cells.

A.–C. UM1 cells were treated with either control mimics or miR-222 mimics for 24 h, and ectopic expression of miR-222 mimics led to significant decreasesin IC50 values A., migration B., and invasion C.. D.–F. UM2 cells were treated with either control LNA or miR-222 LNA for 24 h, and transfection with miR-222 LNA resulted in significant increases in IC50 values D., migration E., and invasion F..*p < 0.05.