Table 3. Prognostic factors affecting overall survival among adrenal cortical carcinoma patients.
| Variable at the time of diagnosis | Univariate Analysis | Multivariate Analysis | HR | 95% CI |
|---|---|---|---|---|
| Year of Diagnosis | NS | |||
| Age at Diagnosis (yr) | ||||
| ≤53 | Reference | |||
| >53 | <0.001 | <0.001 | 1.521 | 1.228–1.885 |
| Sex | NS | |||
| Race | NS | |||
| Marital status | ||||
| Married, Single, Unknown | Reference | |||
| Divorced, Separated, Widowed | 0.009 | 0.038 | 1.343 | 1.016–1.775 |
| Laterality | NS | |||
| Size (mm) | NS | |||
| Clinical stage | ||||
| I/II | Reference | |||
| III | < 0.001 | < 0.001 | 1.932 | 1.527–2.446 |
| Unknown | 0.025 | 0.017 | 1.429 | 1.066–1.916 |
| Tumor Grade | ||||
| I/II | Reference | |||
| III/IV | < 0.001 | 0.005 | 1.966 | 1.226–3.152 |
| Unknown | < 0.001 | 0.005 | 1.792 | 1.195–2.686 |
| Number of Lymph nodes examined | NS (only for lymph node negative cases) | |||
| Radiotherapy | NS | |||