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. 2015 Nov 9;6(42):44995–45004. doi: 10.18632/oncotarget.5707

Table 2a. Characteristics of patients undergoing surgery.

Characteristics Surgery
n = 355
Frequency (%)
Patients <70 years
n = 232
Frequency (%)
Patients ≥70 years
n = 123
Frequency (%)
p-value
Female 161 (45%) 108 (47%) 53 (43%) 0.58
Site 0.21
 Distal Bile Duct 101 (28%) 62 (27%) 39 (32%)
 Gallbladder 103 (29%) 62 (27%) 41 (33%)
 Intrahepatic 72 (20%) 51 (22%) 21 (17%)
 Perihilar 79 (22%) 57 (25%) 22 (18%)
ECOG PS 0.28
 <2 338 (97%) 223 (98%) 115 (96%)
 ≥2 9 (3%) 4 (2%) 5 (4%)
 Missing 8 5 3
Stage 0.82
 I 97 (27%) 66 (29%) 31 (25%)
 II 130 (37%) 82 (36%) 48 (39%)
 III 91 (26%) 58 (25%) 33 (27%)
 IV 36 (10%) 25 (11%) 11 (9%)
 Missing 1 1 0
CCI 0.04
 0 233 (66%) 160 (70%) 73 (60%)
 1 68 (19%) 44 (19%) 24 (20%)
 ≥2 50 (14%) 25 (11%) 25 (20%)
 Missing 4 3 1
Adjuvant Chemotherapy 0.08
 Adjuvant Chemotherapy 74 (21%) 57 (25%) 17 (14%)
 Concurrent Chemotherapy / Radiation 21 (6%) 14 (6%) 7 (6%)
 No Adjuvant Chemotherapy 260 (73%) 161(69%) 99 (80%)

Abbreviations: ECOG PS: European Cooperative Oncology Group Performance Status; CCI: Charlson Co-morbidity index