Table 2b. Characteristics of patients receiving palliative chemotherapy.
| Characteristics | Palliative Chemotherapy n = 274 Frequency (%) |
Patients <70 years n = 206 Frequency (%) |
Patients ≥70 years n = 68 Frequency (%) |
p-value |
|---|---|---|---|---|
| Female | 131 (48%) | 101 (49%) | 30 (44%) | 0.48 |
| Site | 0.008 | |||
| Distal Bile Duct | 53 (19%) | 45 (22%) | 8 (12%) | |
| Gallbladder | 86 (31%) | 65 (32%) | 21 (31%) | |
| Intrahepatic | 74 (27%) | 60 (29%) | 14 (21%) | |
| Perihilar | 61 (22%) | 36 (17%) | 25 (37%) | |
| ECOG PS | 0.009 | |||
| <2 | 259 (92%) | 192 (95%) | 57 (84%) | |
| ≥2 | 22 (8%) | 11 (5%) | 11 (16%) | |
| Missing | 3 | 3 | 0 | |
| Stage | 0.78 | |||
| I | 9 (3%) | 7 (3%) | 2 (3%) | |
| II | 14 (5%) | 9 (4%) | 5 (7%) | |
| III | 31 (11%) | 24 (12%) | 7 (10%) | |
| IV | 219 (80%) | 165 (80%) | 54 (79%) | |
| Missing | 1 | 0 | 1 | |
| CCI | 0.003 | |||
| 0 | 188 (69%) | 150 (73%) | 38 (57%) | |
| 1 | 58 (21%) | 43 (21%) | 15 (22%) | |
| ≥2 | 27 (10%) | 13 (6%) | 14 (21%) | |
| Missing | 1 | 0 | 1 | |
| First-line palliative chemotherapy | 1.00 | |||
| Chemotherapy | 264 (96%) | 198 (96%) | 66 (97%) | |
| Concurrent Chemotherapy/Radiation | 10 (4%) | 8 (4%) | 2 (3%) | |
| Second-line palliative chemotherapy | 0.02 | |||
| Chemotherapy | 72 (27%) | 62 (31%) | 10 (16%) | |
| Concurrent Chemotherapy/Radiation | 4 (1%) | 3 (2%) | 1 (1%) | |
| No second-line Chemotherapy | 192 (72%) | 135 (68%) | 57 (84%) | |
| Missing | 6 | 6 | 0 |
Abbreviations: ECOG PS: European Cooperative Oncology Group Performance Status; CCI: Charlson Co-morbidity index