Table 1.
Baseline Characteristics of Participants According to Furosemide Use and Thiazide Use, Nurses’ Health Study I, 1994.
| No History of Hypertension (n=34,523) | History of Hypertension (n=15,401) | Thiazide No (n=46,678) | Thiazide Yes (n=3,246) | Furosemide No (n=49,323) | Furosemide Yes (n=601) | |
|---|---|---|---|---|---|---|
| Age, years | 57.2 (6.4) | 59.4 (6.4) | 57.8 (6.4) | 59.4 (6.5) | 57.9 (6.5) | 59.8 (6.6) |
| Body mass index, kg/m2 | 25.5 (4.5) | 28.2 (5.6) | 26.2 (4.9) | 28.8 (5.6) | 26.3 (5.0) | 30.0 (6.4) |
| Waist circumference, cm | 84.1 (12.9) | 90.4 (14.3) | 85.6 (13.5) | 91.4 (14.2) | 85.9 (13.6) | 93.1 (16.2) |
| White | 95.0% | 93.1% | 94.6% | 92.7% | 94.5% | 93.7% |
| Physical activity in 2001, METs | 14.3 [5.4–28.5] | 11.5 [4.0–25.0] | 13.5 [5.0–27.5] | 11.7 [4.0–25.0] | 13.5 [5.0–27.4] | 11.6 [3.3–25.1] |
| Smoking status | ||||||
| Never smoker | 46.5% | 46.8% | 46.6% | 47.7% | 46.7% | 42.6% |
| Past smoker | 41.5% | 44.5% | 42.3% | 43.6% | 42.3% | 50.2% |
| Current smoker | 12.0% | 8.5% | 10.9% | 8.6% | 10.8% | 7.0% |
| Alcohol consumption, g/day | 1.8 [0.0–6.5] | 0.9 [0.0–5.3] | 1.5 [0.0–6.2] | 1.0 [0.0–5.8] | 1.5 [0.0–6.1] | 0.9 [0.0–3.5] |
| Daily nutrient intake | ||||||
| Vitamin A, IU | 1521 [840–2553] | 1633 [861–2620] | 1543 [847–2570] | 1647 [860–2630] | 1550 [847–2574] | 1664 [849–2684] |
| Vitamin B12, μg | 8.0 [5.0–12.0] | 8.0 [5.0–12.0] | 8.0 [5.0–12.0] | 8.0 [5.0–12.0] | 8.0 [5.0–12.0] | 8.0 [5.0–13.0] |
| Vitamin C, mg | 213 [136–433] | 220 [143–438] | 214 [138–433] | 227 [147–463] | 215 [138–435] | 226 [155–417] |
| Vitamin E, mg | 14.7 [8.3–114.3] | 15.7 [8.6–182.9] | 14.9 [8.4–115.7] | 16.6 [8.8–186.0] | 15.0 [8.4–116.7] | 17.0 [8.5–185.6] |
| Folate, μg | 404.7 [278.2–634.7] | 414.7 [283.3–648.4] | 406.8 [279.0–637.1] | 422.1 [289.7–633.9] | 408.0 [279.5–639.0] | 408.9 [284.9–620.3] |
| Potassium, mg | 3200 [2571–3907] | 3259 [2620–3999] | 3207 [2577–3921] | 3386 [2710–4171] | 3214 [2583–3932] | 3501 [2708–4283] |
| Magnesium, mg | 334 [266–412] | 336 [267–413] | 335 [266–413] | 336 [270–413] | 335 [267–413] | 330 [260–410] |
| Beta-Carotene, μg | 4570 [3029–7014] | 4695 [3108–7231] | 4604 [3042–7064] | 4759 [3215–7365] | 4614 [3055–7079] | 4626 [3123–7444] |
| Beta-Cryptoxanthin, μg | 155.7 [82.7–235.5] | 170.7 [90.7–244.9] | 159.1 [84.5–237.4] | 178.2 [94.9–251.8] | 160.2 [84.9–238.2] | 176.8 [95.7–250.6] |
| Trans-fats, gm | 2.3 [1.6–3.2] | 2.3 [1.6–3.2] | 2.3 [1.6–3.2] | 2.3 [1.6–3.2] | 2.3 [1.6–3.2] | 2.2 [1.5–3.2] |
| Omega-3 fatty acids, gm | 0.16 [0.09–0.27] | 0.17 [0.10–0.28] | 0.16 [0.09–0.27] | 0.18 [0.10–0.29] | 0.16 [0.10–0.27] | 0.15 [0.09–0.27] |
| History of hypertension | - | - | 27.0% | 86.7% | 30.4% | 71.4% |
| History of diabetes | 2.1% | 7.3% | 3.5% | 6.7% | 3.6% | 12.5% |
| Aspirin use, days/week | ||||||
| <1 | 77.6% | 70.1% | 75.8% | 67.8% | 75.4% | 66.6% |
| 1–3 | 6.2% | 5.6% | 6.0% | 5.9% | 6.0% | 5.2% |
| 4+ | 16.0% | 23.7% | 17.8% | 25.5% | 18.2% | 27.8% |
| Acetaminophen use, days/week | ||||||
| <1 | 84.1% | 79.5% | 83.2% | 75.7% | 82.8% | 71.2% |
| 1–3 | 8.4% | 9.5% | 8.6% | 11.0% | 8.7% | 13.4% |
| 4+ | 5.2% | 7.8% | 5.8% | 9.5% | 5.9% | 11.3% |
| Ibuprofen use, days/week | ||||||
| <1 | 76.9% | 70.6% | 75.7% | 64.5% | 75.1% | 62.2% |
| 1–3 | 9.8% | 9.8% | 9.7% | 11.5% | 9.8% | 9.2% |
| 4+ | 7.6% | 12.2% | 8.6% | 15.0% | 8.9% | 18.8% |
Values are mean (standard deviation), median [interquartile range], or percent
Abbreviations: METs = metabolic equivalents
Waist circumference values were taken from the 1996 questionnaire