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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: Resuscitation. 2016 Feb 6;101:65–70. doi: 10.1016/j.resuscitation.2016.01.024

Table 2.

Serum biomarker concentrations by outcome group and time point.

Median
[IQR], ng/ml		 Controls
(n=43)		 Cardiac arrest
Overall
(n=19)		 Cardiac arrest
Favorable
(n=9)		 Cardiac arrest
Unfavorable
(n=10)		 p-values:
Control vs. Fav
Control vs. Unfav
Fav vs. Unfav
Time point 1
UCH-L1 		0.07 [0.00,0.10] 0.21 [0.14,0.38] 0.21 [0.11,0.23] 0.26 [0.15,0.85] 0.002
<0.001
0.315
Time point 2
UCH-L1 		0.21[0.13,0.94] 0.15 [0.12,0.18] 0.59 [0.27,1.12] 0.001
<0.001
0.006
Time point 1
GFAP 		0.02 [0.00,0.05] 0.00 [0.00,0.00] 0.00 [0.00,0.00] 0.00 [0.00,2.13] 0.0161
0.632
0.156
Time point 2
GFAP 		0.54 [0.00,3.11] 0.00 [0.00,0.49] 2.23 [0.73,16.52] 0.515
<0.001
0.001

UCH-L1, ubiquitin carboxyl-terminal esterase L1; GFAP, glial fibrillary acidic protein; IQR, interquartile range; Fav, favorable outcome 6 months after cardiac arrest; Unfav, unfavorable outcome 6 months after cardiac arrest

1

Serum GFAP concentrations for subjects with cardiac arrest and favorable outcome and controls had levels below detection for the assay