Table 3.
Multivariable Adjusted* Association of Serum Lipid or Lipoprotein Cholesterol Concentrations with BMD at Baseline
| Skeletal Site | Unadjusted Mean (SD) | LDL-c (SD=40) | HDL-c (SD=13) | Triglycerides (SD=59) |
|---|---|---|---|---|
|
| ||||
| Areal BMD (g/cm2) | ||||
| Whole Body | 1.27 (0.11) | 0.003 (0.003) | 0.003 (0.003) | −0.004 (0.003) |
| Total Hip | 1.16 (0.15) | 0.004 (0.004) | −0.002 (0.004) | 0.001 (0.004) |
|
| ||||
| Volumetric BMD (mg/cm3) | ||||
| Cortical, Radius | 1214 (24) | −1.01 (0.67) | 0.55 (0.70) | −0.14 (0.68) |
| Cortical, Tibia | 1178 (25) | −1.11 (0.72) | 0.00 (0.75) | −0.29 (0.73) |
| Trabecular, Radius | 208 (50) | 4.79 (1.41) | −2.69 (1.49) | 3.82 (1.44) |
| Trabecular, Tibia | 227 (41) | 4.45 (1.16) | −3.04 (1.22) | 4.10 (1.17) |
BOLD signifies statistically significant (p<0.05).
Values for multivariable models are presented as β(SE) difference in baseline BMD per 1 standard deviation (SD) higher baseline lipid or lipoprotein cholesterol concentration.
All models are adjusted for baseline age, height, body weight, smoking, alcohol intake, TV watching, diabetes, hypertension, CVD, cancer, having 3+ co-morbid diseases, health status, eGFR and genetic admixture