Table 4.

Multivariable Adjusted^* Association of Serum Lipid or Lipoprotein Cholesterol Concentration with Percent Change in Bone Mineral Density

Skeletal Site	Unadjusted Mean (SD)	LDL-c (SD=40)	HDL-c (SD=13)	Triglycerides (SD=59)
Areal BMD
Whole Body	0.49 (2.36)	0.11 (0.07)	−0.23 (0.07)	0.17 (0.07)
Total Hip	−0.86 (3.36)	0.19 (0.09)	−0.25 (0.10)	0.38 (0.09)
Volumetric BMD
Cortical, Radius	−1.54 (1.35)	−0.02 (0.04)	−0.03 (0.04)	−0.03 (0.04)
Cortical, Tibia	−1.62 (1.19)	−0.02 (0.04)	−0.11 (0.04)	0.08 (0.04)
Trabecular, Radius	−0.22 (4.49)	0.08 (0.14)	−0.25 (0.14)	0.34 (0.14)
Trabecular, Tibia	0.12 (3.60)	0.24 (0.11)	−0.34 (0.11)	0.47 (0.11)

BOLD signifies statistically significant (p<0.05).

Values are displayed as percent change (standard error) in BMD per 1 SD higher baseline serum lipid or lipoprotein cholesterol concentration.

^*All models are adjusted for follow-up time, change in body weight and the following at baseline: corresponding baseline bone measure, age, height, body weight, smoking, alcohol intake, TV watching, diabetes, hypertension, CVD, cancer, having 3+ co-morbid diseases, health status, eGFR and genetic admixture