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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: Environ Mol Mutagen. 2016 Jan 13;57(3):171–189. doi: 10.1002/em.21996

Figure 4.

Figure 4

Fold-increases in γH2AX median channel fluorescence are graphed for each of 67 training set chemicals for both the 4 hr (top panel) and 24 hr (bottom panel) time points. Chemicals are coded according to genotoxic MoA: clastogens = red circles, aneugens = blue squares, and non-genotoxicants = green triangles. A series of data points are plotted for each chemical, as each represents a different concentration. These data highlight the sensitivity of the γH2AX biomarker to clastogenic activity at both the 4 and 24 hr time points.