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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Ann Biomed Eng. 2015 Oct 15;44(3):649–666. doi: 10.1007/s10439-015-1485-2

Figure 9.

Figure 9

(a) FCM imaging of a fluorescently labeled PLGA inverse opal scaffold using an OR-PAM-FCM hybrid system. (b, c) OR-PAM-FCM monitoring of melanoma cells grown on the scaffold, where the cells and scaffold were imaged using the PAM and FCM subsystems, respectively. OR-PAM-OCT images of melanoma cells cultured on an individual PLGA inverse opal scaffold for up to 6 days. (d, e) Coronal and sagittal views of the PAM and PAM/OCT images showing the ingrowth of melanoma cells from the surface into the center of the scaffold using the OR-PAM-OCT hybrid system. The melanoma cells were imaged by the PAM subsystem whereas the scaffold by the OCT subsystem in a label-free manner. (f) Volumetric rendering of the OCT-imaged scaffold (gray) with PAM-detected melanoma cells (red).