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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Life Sci. 2016 Feb 11;148:106–111. doi: 10.1016/j.lfs.2016.02.047

Figure 3.

Figure 3

Effect of daily manganese (Mn) supplementation on basal prostaglandin E2 (PGE2) release from prepubertal female rats after short term ALC exposure.

The same four treatment groups of animals as described in Figure 1 were used. On day 31 the medial basal hypothalamus (MBH) of animal was excised and incubated in vitro. Note that Mn stimulates PGE2 and subsequently LHRH release, even in the presence of ALC. Panel A: a vs b and c, p<0.05; b vs c, p<0.01; b vs d, p<0.05; c vs d, p<0.05; Bars with same letters are not different. Panel B: a vs b, p<0.01; a vs c, p<0.05; b vs c, p<0.01; b vs d, p<0.05; c vs d, p<0.05. N=10-12 animals per group.